Autophagy, Inflammation, and Metabolism (AIM) Center in its second year
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چکیده
منابع مشابه
Autophagy and its Role in Metabolism
Macroautophagy (hereafter autophagy) is a cellular quality control mechanism that evolved to recycle cellular waste and maintain energy homeostasis under starvation. However, its implications in regulating metabolism has only recently begun to be uncovered. Recent studies have revealed new functions of autophagy such as sensing damaged tissue mitochondria and preventing cellular injury by remov...
متن کاملAOJNMB in its second year of publication
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
متن کاملAutophagy and inflammation
Autophagy is a homeostatic mechanism involved in the disposal of damaged organelles, denatured proteins as well as invaded pathogens through a lysosomal degradation pathway. Recently, increasing evidences have demonstrated its role in both innate and adaptive immunity, and thereby influence the pathogenesis of inflammatory diseases. The detection of autophagy machinery facilitated the measureme...
متن کاملAutophagy, Metabolism, and Cancer
Macroautophagy (autophagy hereafter) is a process that collects cytoplasmic components, particularly mitochondria, and degrades them in lysosomes. In mammalian systems, basal autophagy levels are normally low but are profoundly stimulated by starvation and essential for survival. Cancer cells up-regulate autophagy and can be more autophagy-dependent than most normal tissues. Genetic deficiency ...
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ژورنال
عنوان ژورنال: Autophagy
سال: 2019
ISSN: 1554-8627,1554-8635
DOI: 10.1080/15548627.2019.1634444